Tuberculosis-immune Reconstitution Inflammatory Syndrome
نویسندگان
چکیده
منابع مشابه
Immune reconstitution inflammatory syndrome in CNS tuberculosis.
BACKGROUND Immune Reconstitution Inflammatory Syndrome (IRIS), an exaggerated inflammatory response with clinical worsening due to immune recovery during treatment, is rare in the immune-competent population. CASE CHARACTERISTICS A 5-½-year old immune-competent girl with CNS tuberculosis without HIV who developed paradoxical IRIS. OUTCOME Response to supportive care along with Anti-tubercul...
متن کاملImmune reconstitution inflammatory syndrome.
Immune reconstitution inflammatory syndrome (IRIS) is a collection of inflammatory disorders associated with paradoxical worsening of preexisting infectious processes after the initiation of highly active antiretroviral therapy (HAART) in human immunodeficiency virus (HIV)-infected individuals. At the initial stage of the disease, the imaging findings can be misdiagnosed as pneumonia resulting ...
متن کاملHypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome.
Increased access to combination antiretroviral therapy in areas co-endemic for tuberculosis (TB) and HIV-1 infection is associated with an increased incidence of immune reconstitution inflammatory syndrome (TB-IRIS) whose cause is poorly understood. A case-control analysis of pro- and anti-inflammatory cytokines in TB-IRIS patients sampled at clinical presentation, and similar control patients ...
متن کاملCytotoxic Mediators in Paradoxical HIV–Tuberculosis Immune Reconstitution Inflammatory Syndrome
Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) frequently complicates combined antiretroviral therapy and antituberculosis therapy in HIV-1-coinfected tuberculosis patients. The immunopathological mechanisms underlying TB-IRIS are incompletely defined, and improved understanding is required to derive new treatments and to reduce associated morbidity and mortality....
متن کاملTuberculosis immune reconstitution inflammatory syndrome: profile of an enigmatic condition
Tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) in HIV co-infected TB patients is an intriguing but frequently occurring phenomenon experienced by patients after initiating anti retroviral therapy. It is characterized by paradoxical worsening of clinical and radiological manifestations of TB, after initiation of highly active antiretroviral therapy, when improvement in the ge...
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 2020
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.3580-19